Spruce Biosciences, Inc. (SPRB)

Spruce Biosciences, Inc. at a glance — key fundamentals, SEC filings, insider buying and selling, and earnings dates.

Spruce Biosciences, Inc. (SPRB) is a Biotechnology company based in US with a market capitalization of $68.2M. Free cash flow was negative at -$33.3M. This page tracks SPRB's SEC filings, insider buying and selling, earnings dates, and key fundamentals in one place.

US · 20 employees · IPO Oct 9, 2020

Valuation

Valuation & price

$53.78 · as of May 17, 2026 · -70.5% vs 52w high

P/E ratio

Latest-FY diluted EPS

1.60

P/B ratio

Market cap ÷ book equity

Dividend yield

Price — last 12 months

$177$91.08$5.25Jul 25Dec 25Jul 26Jul 7, 25$5.25Jul 9, 25$5.48Jul 11, 25$6.68Jul 15, 25$7.28Jul 17, 25$7.13Jul 21, 25$8.70Jul 23, 25$9.30Jul 25, 25$8.78Jul 29, 25$8.93Jul 31, 25$8.25Aug 4, 25$9.00Aug 6, 25$10.13Aug 11, 25$9.15Aug 13, 25$9.30Aug 15, 25$9.01Aug 19, 25$8.91Aug 21, 25$8.50Aug 25, 25$7.95Aug 27, 25$7.48Aug 29, 25$7.00Sep 3, 25$8.15Sep 5, 25$9.00Sep 9, 25$9.00Sep 11, 25$8.80Sep 16, 25$9.58Sep 18, 25$8.88Sep 22, 25$9.08Sep 24, 25$8.35Sep 26, 25$7.75Sep 30, 25$8.95Oct 2, 25$8.60Oct 6, 25$130.40Oct 8, 25$160.07Oct 10, 25$173.60Oct 14, 25$176.91Oct 16, 25$156.61Oct 21, 25$129.54Oct 23, 25$129.92Oct 27, 25$123.02Oct 29, 25$118.00Oct 31, 25$110.10Nov 4, 25$104.94Nov 6, 25$119.29Nov 10, 25$115.61Nov 12, 25$102.20Nov 14, 25$106.35Nov 18, 25$115.00Nov 20, 25$102.61Nov 25, 25$104.57Nov 28, 25$100.00Dec 2, 25$89.20Dec 4, 25$90.44Dec 8, 25$81.68Dec 10, 25$85.67Dec 12, 25$83.40Dec 16, 25$78.00Dec 18, 25$76.77Dec 22, 25$82.82Dec 24, 25$84.00Dec 29, 25$82.30Jan 2, 26$90.70Jan 6, 26$80.57Jan 8, 26$73.70Jan 12, 26$77.80Jan 14, 26$78.37Jan 16, 26$73.53Jan 21, 26$78.92Jan 23, 26$81.52Jan 27, 26$84.24Jan 29, 26$79.86Feb 2, 26$77.99Feb 4, 26$79.23Feb 9, 26$79.07Feb 11, 26$82.69Feb 13, 26$66.29Feb 18, 26$53.48Feb 20, 26$49.72Feb 24, 26$58.22Feb 26, 26$58.55Mar 2, 26$54.21Mar 4, 26$57.54Mar 6, 26$55.87Mar 10, 26$62.79Mar 12, 26$59.90Mar 17, 26$64.30Mar 19, 26$59.05Mar 23, 26$58.83Mar 25, 26$69.97Mar 27, 26$63.04Mar 31, 26$65.35Apr 2, 26$70.50Apr 7, 26$62.15Apr 9, 26$66.01Apr 13, 26$64.51Apr 15, 26$69.32Apr 17, 26$70.30Apr 22, 26$52.36Apr 24, 26$54.37Apr 28, 26$54.77Apr 30, 26$57.32May 4, 26$59.37May 6, 26$57.87May 8, 26$56.50May 12, 26$56.67May 14, 26$59.00May 18, 26$51.41May 20, 26$51.52May 22, 26$51.08May 28, 26$49.19Jun 1, 26$50.70Jun 3, 26$49.05Jun 5, 26$50.43Jun 9, 26$49.03Jun 11, 26$49.11Jun 15, 26$49.91Jun 17, 26$48.76Jun 22, 26$54.70Jun 24, 26$51.87Jun 26, 26$55.11Jul 2, 26$52.51
$5.2552-week range$182.60
Loading valuation history…

Fundamentals

Key fundamentals

$68.2M

Market cap

Revenue growth (YoY)

100.0%

Gross margin

-$33.3M

Free cash flow (USD)

-$48.2M

Net debt

Net cash position

42.9%

Share dilution

2/5

Graham criteria passed

Defensive-investor screen

Healthcare

Sector

Trajectory

Long-term trends

Revenue by year

20182025

FY 2018$0.00FY 2019$0.00FY 2020$0.00FY 2021$0.00FY 2022$0.00FY 2023$10.1MFY 2024$4.9MFY 2025$0.00
$0$0

Free cash flow by year

20182025

FY 2018$-8.6MFY 2019$-12.6MFY 2020$-27.6MFY 2021$-36.0MFY 2022$-41.7MFY 2023$-33.3MFY 2024$-56.0MFY 2025$-33.3M
-$8.6M-$33.3M

Gross margin by year

20232024

FY 2023100.0%FY 2024100.0%
100.0%100.0%

Value screen

Graham defensive-investor tests

Computing the scorecard — refreshing any stale inputs…

0

Insider buys · 90 days

0

Insider sells · 90 days

Earnings

Last report: 10-Q filed May 13, 2026

Next expected: not yet scheduled

On the tape

Recent SEC & insider activity

  • 8-K eventAnnual Meeting ResultsMay 26, 2026Filing
  • 8-K eventFinancial Results ReportedMay 13, 2026Filing
  • Quarterly report10-Q FiledMay 13, 2026Filing
  • 8-K eventPublic Offering AnnouncedApr 22, 2026Filing

Questions

Frequently asked questions

What is Spruce Biosciences, Inc.'s market cap?

Spruce Biosciences, Inc. (SPRB) has a market capitalization of $68.2M.

What is SPRB's P/E ratio?

A meaningful P/E ratio is not available for SPRB — the company's latest fiscal-year earnings per share is zero, negative, or not yet cached.

What is SPRB's price-to-book (P/B) ratio?

SPRB trades at 1.60 times book value per share.

Are insiders buying SPRB stock?

SEC Form 4 filings show no open-market insider buys at Spruce Biosciences, Inc. in the last 90 days (0 sells).

Same arena

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Timeline

Every filing, insider trade & earnings on a price-anchored timeline

Filing Analyzer

Search the actual 10-K / 10-Q text with AI research angles

News

Latest press coverage in one feed

Data: SEC EDGAR filings and cached fundamental data; prices and ratios use the most recent cached quote and statements (may lag by up to a day). Educational and research purposes only. Not investment advice.