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Prime Medicine, Inc. (PRME)

Prime Medicine, Inc. at a glance — key fundamentals, SEC filings, insider buying and selling, and earnings dates.

Prime Medicine, Inc. (PRME) is a Biotechnology company based in US with a market capitalization of $632.2M. Free cash flow was negative at -$167.1M. This page tracks PRME's SEC filings, insider buying and selling, earnings dates, and key fundamentals in one place.

US · 214 employees · IPO Oct 20, 2022

Valuation

Valuation & price

$2.93 · as of May 17, 2026 · -56.1% vs 52w high

—

P/E ratio

Latest-FY diluted EPS

5.23

P/B ratio

Market cap ÷ book equity

—

Dividend yield

Price — last 12 months

$6.37$4.54$2.70Jul 25Dec 25Jun 26Jul 7, 25$3.80Jul 9, 25$4.54Jul 11, 25$4.35Jul 15, 25$4.29Jul 17, 25$3.90Jul 21, 25$4.57Jul 23, 25$4.64Jul 25, 25$4.21Jul 29, 25$3.83Jul 31, 25$3.74Aug 4, 25$4.50Aug 6, 25$4.07Aug 8, 25$3.79Aug 12, 25$3.46Aug 14, 25$3.64Aug 18, 25$3.50Aug 20, 25$3.24Aug 22, 25$3.55Aug 26, 25$3.63Aug 28, 25$3.44Sep 3, 25$3.34Sep 5, 25$3.72Sep 9, 25$4.12Sep 11, 25$4.08Sep 15, 25$4.01Sep 17, 25$4.65Sep 19, 25$4.89Sep 23, 25$5.39Sep 25, 25$5.22Sep 29, 25$5.32Oct 1, 25$5.59Oct 3, 25$6.32Oct 7, 25$5.87Oct 9, 25$6.23Oct 13, 25$5.65Oct 15, 25$6.37Oct 17, 25$5.45Oct 21, 25$5.59Oct 23, 25$5.38Oct 27, 25$5.15Oct 30, 25$4.35Nov 3, 25$4.56Nov 5, 25$4.40Nov 7, 25$3.81Nov 11, 25$3.92Nov 13, 25$3.33Nov 17, 25$3.82Nov 19, 25$3.72Nov 21, 25$3.63Nov 25, 25$3.72Nov 28, 25$3.82Dec 2, 25$3.30Dec 4, 25$3.85Dec 8, 25$4.21Dec 10, 25$4.33Dec 12, 25$4.10Dec 16, 25$3.88Dec 18, 25$3.60Dec 22, 25$3.70Dec 24, 25$3.57Dec 29, 25$3.37Jan 2, 26$3.53Jan 6, 26$3.70Jan 8, 26$3.92Jan 12, 26$4.28Jan 14, 26$4.31Jan 16, 26$3.98Jan 21, 26$4.01Jan 23, 26$4.43Jan 27, 26$4.28Jan 29, 26$4.15Feb 2, 26$3.80Feb 4, 26$3.48Feb 6, 26$3.57Feb 10, 26$3.42Feb 12, 26$3.32Feb 17, 26$3.31Feb 19, 26$3.33Feb 23, 26$3.34Feb 25, 26$4.13Mar 2, 26$4.66Mar 4, 26$4.12Mar 6, 26$4.01Mar 10, 26$4.05Mar 12, 26$3.73Mar 16, 26$3.67Mar 18, 26$3.53Mar 20, 26$3.52Mar 24, 26$3.52Mar 26, 26$3.64Mar 30, 26$3.15Apr 1, 26$3.39Apr 6, 26$3.34Apr 8, 26$3.54Apr 10, 26$3.43Apr 14, 26$3.70Apr 16, 26$3.67Apr 20, 26$3.89Apr 22, 26$3.96Apr 24, 26$3.70Apr 28, 26$3.69May 1, 26$3.41May 5, 26$3.39May 7, 26$3.12May 11, 26$3.24May 13, 26$3.27May 15, 26$2.93May 19, 26$2.70May 21, 26$2.95May 26, 26$2.97May 28, 26$3.40Jun 1, 26$3.40Jun 3, 26$3.14Jun 5, 26$3.06Jun 9, 26$2.88Jun 11, 26$2.82Jun 15, 26$2.90Jun 17, 26$3.16Jun 22, 26$3.37Jun 26, 26$3.43
$2.7052-week range$6.67
Loading valuation history…

Fundamentals

Key fundamentals

$632.2M

Market cap

—

Revenue growth (YoY)

-58.0%

Gross margin

-$167.1M

Free cash flow (USD)

-$61.3M

Net debt

Net cash position

25.4%

Share dilution

0/5

Graham criteria passed

Defensive-investor screen

Healthcare

Sector

Trajectory

Long-term trends

Revenue by year

2019 → 2025

FY 2019$0.00FY 2020$5.2MFY 2021$0.00FY 2022$0.00FY 2023$0.00FY 2024$3.0MFY 2025$4.6M
$0$4.6M

Free cash flow by year

2019 → 2025

FY 2019$-1.3MFY 2020$-6.2MFY 2021$-38.2MFY 2022$-147.9MFY 2023$-174.1MFY 2024$-130.2MFY 2025$-167.1M
-$1.3M-$167.1M

Gross margin by year

2024 → 2025

FY 2024100.0%FY 2025-58.0%
100.0%-58.0%

Value screen

Graham defensive-investor tests

Computing the scorecard — refreshing any stale inputs…

0

Insider buys · 90 days

0

Insider sells · 90 days

Earnings

Last report: 10-Q filed May 7, 2026

Next expected: not yet scheduled

On the tape

Recent SEC & insider activity

  • 8-K eventAnnual Meeting ResultsJun 8, 2026Filing
  • 8-K eventCFO AppointmentMay 7, 2026Filing
  • Quarterly report10-Q FiledMay 7, 2026Filing
  • 8-K eventCFO AppointmentApr 16, 2026Filing

Questions

Frequently asked questions

What is Prime Medicine, Inc.'s market cap?

Prime Medicine, Inc. (PRME) has a market capitalization of $632.2M.

What is PRME's P/E ratio?

A meaningful P/E ratio is not available for PRME — the company's latest fiscal-year earnings per share is zero, negative, or not yet cached.

What is PRME's price-to-book (P/B) ratio?

PRME trades at 5.23 times book value per share.

Are insiders buying PRME stock?

SEC Form 4 filings show no open-market insider buys at Prime Medicine, Inc. in the last 90 days (0 sells).

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Timeline

Every filing, insider trade & earnings on a price-anchored timeline

Filing Analyzer

Search the actual 10-K / 10-Q text with AI research angles

News

Latest press coverage in one feed

Data: SEC EDGAR filings and cached fundamental data; prices and ratios use the most recent cached quote and statements (may lag by up to a day). Educational and research purposes only. Not investment advice.